Epidural clonidine utilized being an adjunct to regional anesthetics has three distinct mechanisms of action. Initially, the stimulation of alpha-2-receptors from the dorsal horn cuts down pain transmission. Next, clonidine may cause nearby vasoconstriction that limits vascular elimination of local epidural anesthetics. : connected to, served by, or out https://www.proleviate.com/post/the-new-pain-killer-conolidine